Publications récentes & Brevets

Publications récentes & Brevets

Publications récentes & Brevets

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Publications sélectionnées (2024-2011)


Touaibia, M.; Chiasson, A I.; Robichaud, S.; Doiron, J A.; Hébert, M P A.; Surette, M E. (2024). Single and multiple inhibitors of the biosynthesis of 5-, 12-, 15-lipoxygenase products derived from cinnamyl-3,4-dihydroxy-α-cyanocinnamate: synthesis and structure-activity relationship. Drug Development Research, 85, e22181, 1-17.

Ayad, S A; Hébert, M P A; Doiron, J A; Loucif-Ayad, W; Daas, T; Smagghe, G; Alburaki, M; Barnett, D A; Touaibia, M,; Surette, M E. (2024). Algerian propolis from distinct geographical locations:  chemical profiles, antioxidant capacity, cytotoxicity and inhibition of 5-lipoxygenase product biosynthesis. Chem. Biodiversity e202301758, 1-13.

Mora, N; Rosa, M; Touaibia, M; Martin, L J. (2024). Effects of Red Sorghum-Derived Deoxyanthocyanidins and their O-β-D-Glucosides on E-Cadherin Promoter Activity in PC-3 Prostate Cancer Cells. Molecules, 29, 1891, 1-13.

Luc J. Martin J. L.; 1, Touaibia, M. (2024). Prevention of Male Late-Onset Hypogonadism by Natural Polyphenolic Antioxidants. Nutrients, 16(12), 1815.

Touaibia, M. Grosset-Magagne, M. (2024) Synthesis of 3,4-bis[(2,3,4,6-tetra-O-acetyl-ß-D-glucopyranosyl)oxy] benzaldehyde. Carbohydrate Chemistry: Proven Synthetic Methods, Volume 6, Ed.: Giguère, D.; Vincent, S. P.; CRC Press, accepted (invited contribution)


Basque, A; Touaibia, M; Martin, L J. (2023). Sinapic and ferulic acid phenethyl esters increase the expression of steroidogenic genes in MA-10 tumor Leydig cells. Toxicology In Vitro, 86, 105505.

Cormier, R J.; Doiron, J A.; Touaibia, M; Surette, M E.; Pichaud, N. (2023). Time-dependent metabolome and fatty acid profile changes following a high-fat diet exposure in Drosophila melanogaster. Insect Biochemistry and Molecular Biology, 152, 103892.

Hebert, M P. A.; Selka, A; Lebel, A A.; Doiron, J A. ; Chiasson, A I; Gauvin, V L. ; Matthew, A J.; Hebert, M J. G.; Doucet, M S.; Joy, A P. ; Barnett, D A.; Touaibia, M; Surette, M E. ; Boudreau, L H. (2023). Caffeic acid phenethyl ester analogues as selective inhibitors of 12-lipoxygenase product biosynthesis in human platelets. International Immunopharmacology, 121, 110419.

Wontcheu Fotso, Y A.; Ghazi, S.; Belkaid, A.; Soucy, J.; Tremblay, L.; Lamarre, S.; Clarisse, O.; Touaibia, M. (2023). Extraction, Chemical Composition, Antiradical Capacity, and Photoprotective Effect of Inonotus obliquus from Eastern Canada. Nutraceuticals, 3(3), 380-402.

Ducros, L.; Touaibia, M.; Pichaud, N.; Lamarre, S.G. (2023). Resilience and phenotypic plasticity of Arctic char (Salvelinus alpinus) facing cyclic hypoxia: insights into growth, energy stores and hepatic metabolism. Conservation Physiology, 11, 1, coad099.


Selka, A; Ndongou Moutombi, F.J.; Jean-François, J.; Touaibia, M. (2022). Hydroxycinnamic acids and their related synthetic analogs: an update of pharmacological activities. Mini-Reviews in Medicinal Chemistry.  2022, 22, 1516-1544.

Bhullar, K S.; Nael, M A.; Elokely, K M. ; Doiron, J A.; LeBlanc, L M.; Lassalle-Claux, G; Salla, M; Aldawsari, F S.; Touaibia, M ; Rupasinghe, H. P. V. (2022). Ketone Analog of Caffeic Acid Phenethyl Ester Exhibits Antioxidant Activity via Activation of ERK-Dependent Nrf2 Pathway.  Applied Sciences, 12(6), 3062.

Basque, A; Nguyen, H T ; Touaibia, M ; Martin, L J. (2022). Gigantol Improves Cholesterol Metabolism and Progesterone Biosynthesis in MA-10 Leydig Cells. Current Issues in Molecular Biology, 44(1), 73-93.

Touaibia, M ; Faye, D C; Doiron, J A.; Chiasson, A I; Blanchard, S; Roy, P P; Surette, M E. (2022). Structure-Activity Relationship Studies of New Sinapic Acid Phenethyl Ester Analogues Targeting the Biosynthesis of 5-Lipoxygenase Products: The Role of Phenolic Moiety, Ester Function, and Bioisosterism. Journal of Natural Products, 85(1), 225-236.

Johnson, Mathieu; Nowlan, Sarah; Sahin, Gulsum; Barnett, David A.; Joy, Andrew P.; Touaibia, M; Cuperlovic-Culf, M; Avizonis, D Z; Turcotte, S. (2022) Decrease of intracellular glutamine by STF-62247 results in the accumulation of lipid droplets in von Hippel-Lindau deficient cells. Frontiers in Oncology, 12, 841054.


Touaibia, M; Fabiano-Tixier, A-S; Chemat, F. (2021) Chloropinane and chloromenthene as novel solvents for solubilisation of natural products Molbank, (2), M1205. 

Nguyen, H T; Couture, R; Touaibia, M; Martin, L J. (2021). Transcriptome modulation by addition of luteolin to BEP chemotherapy on rat LC540 tumor Leydig cells. Andrologia, 53(2), e13960

Cormier, R J; Strang, R;  Menail, H; Touaibia, M; Pichaud, N. (2021) Systemic and mitochondrial effects of metabolic inflexibility induced by high fat diet in Drosophila melanogaster, Biochemistry and Molecular Biology, 133, 103556.

Touaibia, M ; St-Coeur, P D; Duff, P; Faye, D C; Pichaud, N. (2021). 5-Benzylidene, 5-benzyl, and 3-benzylthiazolidine-2,4-diones as potential inhibitors of the mitochondrial pyruvate carrier: Effects on mitochondrial functions and survival in Drosophila melanogaster. European Journal of Pharmacology, 913, 174627.


Ndongou Moutombi, FJ; Fabiano-Tixier, AS; Clarisse, O; Chemat, F; Touaibia, M. (2020). Partial and Total Solvent-Free Limonene’s Hydrogenation: Metals, Supports, Pressure, and Water Effects. Journal of Chemistry. 2020: 1-11.

Simard, CJ; Touaibia, M; Allain, EP; Hebert-Chatelain, E; Pichaud, N. (2020). Role of the mitochondrial pyruvate carrier in the occurrence of metabolic inflexibility in Drosophila melanogaster exposed to dietary sucrose. Metabolites 2020, 10, 411. 10(411): 1-21.

Couture R, Mora N, Al Bittar S, Najih M, Touaibia M, Martin L J. (2020). Luteolin modulates gene expression related to steroidogenesis, apoptosis and stress response in rat LC540 tumor Leydig cells. Cell Biology and Toxicology. 36: 31-49.

Selka, A; Ndongou Moutombi, FJ; Cormier, M; Touaibia, M. (2020). Phenethyl esters of ferulic acid, hydroferulic acid,homovanillic acid, and vanillic acid: synthesis, free radicals scavengingactivity, and molecular modeling as potential cholinesterases inhibitors. Molbank 2020, 2020(3), M1151. 2020(3): M1151.

Sambou, M; Jean-François, J; Ndongou Moutombi, F J;, Doiron, J A; Hébert, MPA; Joy, A p; Mai-Thi, N; Barnett, D A; Surette M E;. Boudreau, L H; Touaibia, M. (2020). Extraction, Antioxidant Capacity, 5-Lipoxygenase Inhibition, and Phytochemical Composition of Propolis from Eastern Canada. Molecules. 25(2397): 1-20.

Murugesan, A; Lassalle-Claux, G; Hogan, L; Vaillancourt, E; Selka, A; Luiker, K; Kim, MJ; Touaibia, M; Reiman, T. (2020). Antimyeloma Potential of Caffeic Acid Phenethyl Ester and its Analogs through Sp1 Mediated Downregulation of IKZF1-IRF4-MYC Axis. Journal of Natural Products, 83, 3526-3535.

Simard, C; Lebel, A; Allain, E P Touaibia, M; Hebert-Chatelain, E; Pichaud, N. (2020). Metabolic Characterization and Consequences of Mitochondrial Pyruvate Carrier Deficiency in Drosophila melanogaster. Metabolites. 10(9): 363.

Martin, LJ; Touaibia, M. (2020). Improvement of Testicular Steroidogenesis Using Flavonoids and Isoflavonoids for Prevention of Late-Onset Male Hypogonadism. Antioxidants. 9(237): 1-17.

Touaibia, M; Selka, A; Levesque, N; St-Onge, P. (2020). Green Hydrogenation: Solvent-Free Hydrogenation of Pinenes for An Undergraduate Organic Chemistry Laboratory. Journal of Chemical Education. 97(8): 2296-2301.

Chiasson, AI; Robichaud, S; Ndongou Moutombi, FJ; Hébert MPA.; Mbarik M; Surette ME; Touaibia M. (2020). New zileuton-hydroxycinnamic acid hybrids: synthesis and structure-activityrelationship towards 5-lipoxygenase inhibition. Molecules 2020, 25, 4686. 25(4686): 1-18.


Selka, A; Doiron, J A.; Lyons, P; Dastous, S; Chiasson, A; Cormier, M; Turcotte, S; Surette, M E.; Touaibia, M. (2019). Discovery of a novel 2, 5-dihydroxycinnamic acid-based 5-lipoxygenase inhibitor that induces apoptosis and may impair autophagic flux in RCC4 renal cancer cells. European Journal of Medicinal Chemistry, 179, 347-357. 

Couture R, Mora N, Al Bittar S, Najih M, Touaibia M, Martin L J. (2019). Luteolin modulates gene expression related to steroidogenesis, apoptosis and stress response in rat LC540 tumor Leydig cells. Cell Biology and Toxicology.

Doucet MS, Jougleux JL, Poirier SJ, Cormier M, Léger JL, Surette ME, Pichaud N, Touaibia M, Boudreau LH. (2019). Identification of peracetylated quercetin as a selective 12-lipoxygenase pathway inhibitor in human platelets. Molecular Pharmacology, 95(1), 139-150.

Mbarik, M; Poirier, Samuel J.; Doiron, J; Selka, A; Barnett, D A.; Cormier, M; Touaibia, M; Surette, M E. (2019). Phenolic acid phenethylesters and their corresponding ketones: Inhibition of 5-lipoxygenase and stability in human blood and HepaRG cells. Pharmacology Research & Perspectives, 7(5), e00524.

LeBlanc A, Cuperlovic-Culf M, Morin PJ, Touaibia M. (2019). Structurally Related Edaravone Analogues: Synthesis, Antiradical, Antioxidant, and Copper-Chelating Properties. CNS Neurol. Disord. Drug Targets, 18(10), 779-790.


Ndongou Moutombi FJ, Selka A, Fabiano-TIXIER AS, Foucher D, Clarisse O, Chemat F, Touaibia M. (2018). Highly selective solvent-free hydrogenation of pinenes to added value cis-pinane. Comptes Rendus Chimie, 21(11), 1035-1042

Mousavifar L, Touaibia M, Roy R. (2018). Development of Mannopyranoside Therapeutics Against Adherent-invasive E. coli Infections. Accounts of Chemical Research, 51(11), 2937-2948.

D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC. (2018). Autotaxin-Lysophosphatidic Acid Signaling Contributes to Obesity-Induced Insulin Resistance in Muscle and Impairs Mitochondrial Metabolism. Journal of Lipid Research, 59(10), 1805-1817.

Cormier M, Ghouili F, Roumaud P, Bauer W, Touaibia M, Martin L J. (2018). Influences of flavones on cell viability and cAMP-dependent steroidogenic genes regulation in MA-10 Leydig cells. Cell Biology and Toxicology, 34(1), 23-38.

Touaibia M, Hébert MJG, Levesque NA, Doiron JA, Doucet MS, Jean-François J, Cormier M, Boudreau LH, Surette ME. (2018). Sinapic Acid Phenethyl Ester as a Potent Selective 5-Lipoxygenase Inhibitor: Synthesis and Structure Activity Relationship. Chemical Biology & Drug Design, 92(5), 1876-1887.


M. Touaibia, E-M. Krammer, T.C. Shiao, N. Yamakawa, Q. Wang, A. Glinschert, A. Papadopoulos, L. Mousavifar, E. Maes, S. Oscarson, G. Vergoten, M. F. Lensink, R. Roy, J. Bouckaert (2017) Sites for Dynamic Protein-Carbohydrate Interactions of O- and C-Linked Mannosides on the E. coli FimH Adhesin. Molecules, 22(7), 1101/1-1101/18.

M. Cormier; F. Ghouili; P. Roumaud; L. J. Martin; M. Touaibia (2017) Influence of flavonols and quercetin derivative compounds on MA-10 Leydig cells steroidogenic genes expressions. Toxicology in Vitro, 44, 111-121.

P. Jr Morin, P.-D. St-Coeur, J. A. Doiron, M. Cormier, J. J. Poitras, M. E. Surette, M. Touaibia (2017) Substituted Caffeic and Ferulic Acid Phenethyl Esters: Synthesis, Leukotrienes Biosynthesis Inhibition and Cytotoxic Activity. Molecules, 22(7), 1124/1-1124/17.

L. H. Boudreau, G. Lassalle-Claux, M. Cormier, S. Blanchard, M. S. Doucet, M. E. Surette and M. Touaibia (2017) New hydroxycinnamic acid esters as novel 5-lipoxygenase inhibitors that affect leukotriene biosynthesis. Mediators of Inflammation, 6904634, 1-12.

J. A. Doiron, L. M. Leblanc, M. J. G. Hébert, N. A. Levesque, A. F. Paré, J. Jean-François, M. Cormier, M. E. Surette, M. Touaibia (2017) Structure activity relationship of caffeic acid phenethyl ester analogs as new 5-lipoxygenase inhibitors. Chemical Biology & Drug Design, 89(4), 514-528.

P-P. Roy, D. Faye, S. Blanchard, M. Cormier, J. A. Doiron, M. E. Surette, M. Touaibia. (2017) New caffeic acid phenylethyl ester analogues bearing substituted triazole: Synthesis and structure-activity relationship study towards 5-Lipoxygenase inhibition. Journal of Chemistry, vol. 2017, Article ID 2380531, 1-11, doi:10.1155/2017/2380531.

M. Cormier, F. Ghouili, P. Roumaud, W. Bauer, M. Touaibia, L. J. Martin. (2017) Influences of flavones on cell viability and cAMP-dependent steroidogenic gene regulation in MA-10 Leydig cells. Cell Biol Toxicol, In press (DOI 10.1007/s10565-017-9395-8)

K. D’Souza; D. A. Kane; M. Touaibia; E. E. Kershaw; T. Pulinilkunnil; P. C. Kienesberger (2017) Autotaxin is Regulated by Glucose and Insulin in Adipocytes. Endocrinology, 158(4), 791-803.

Selka, A; Levesque, N; Foucher, D; Clarisse, O; Chemat, F; Touaibia, Mohamed (2017) A Comparative Study of Solvent-Free and Highly Efficient Pinene Hydrogenation over Pd on Carbon, Alumina, and Silica Supports. Organic Process Research & Development, 21(1), 60-64.

P-D. St-Coeur, M. Cormier, V. C. LeBlanc, P. Jr Morin, M. Touaibia (2017) Effect of O6-substitued guanine analogs on O6-methylguanine DNA-methyltransferase expression and glioblastoma cells viability. Medicinal Chemistry. 13(1), 28-397.


E. Yara-Varón, A. Selka, A.S Fabiano-Tixier, M. Balcells, R. Canela-Garayoa Antoine Bily, M. Touaibia, F. Chemat (2016) Green solvent from forestry biomass. Pinane a stable terpene derived from pine trees by product to substitute n-hexane for the extraction of bioactive compounds. Green Chemistry. 18(24), 6596-6608.

Batoul Benyelles, Hocine Allali, Mohamed Touaibia, Nadia Fekih, Luc H. Boudreau, Marc E. Surette (2016) Antioxidant and anti-inflammatory activities of the volatile components of Tropaeolum majus L. (Garden Nasturtium) from north western Algeria. Journal of Pharmaceutical, Chemical and Biological Sciences, 4(3), 431-439

Adrian Culf, Daniel Leger, Martin Leger, Rodney Ouellette, David Barnett, Mohamed Touaibia (2016) Zwitterionic Azaspirocyclic Hydantoins. Letters in Organic Chemistry. 13(8), 566-571.

Pierre-Philippe Roy, Kenneth D'Souza, Miroslava Cuperlovic-Culf, Petra C. Kienesberger and Mohamed Touaibia (2016) New Atglistatin closely related analogues: synthesis and structure-activity relationship towards adipose triglyceride lipase. inhibition. European Journal of Medicinal Chemistry, 118, 290-298.

Anissa Belkaid, Miroslava Cuperlovic-Culf, Mohamed Touaibia, Rodney Ouellette, Marc Surette (2016) Metabolic effect of estrogen receptor agonists on breast cancer cells in the presence or absence of carbonic anhydrase inhibitors. Metabolites, 6(2), 16.

Cuperlovic-Culf M, Cormier K, Touaibia M, Reyjal J, Robichaud S, Belbraouet M and Turcotte S. (2016) 1H NMR Metabolomics analysis of renal cell carcinoma cells: VHL and HIF effects on metabolism. International J. Cancer 138(10):2439-2449.


Chenqi Zhao, Uriel Moreno-Nieves, J. Di Battista, Maria J. Fernandes, MohamedTouaibia, Sylvain G. Bourgoin. (2015) Chemical hypoxia brings to light altered autocrine sphingosine-1-phosphate signalling in rheumatoid arthritis synovial fibroblasts. Mediators of Inflammation. In press

S. Balaji, M. Thibault, Y. Djaoued, C. Pelletier, M. Touaibia, N. Tchoukanova. (2015) Chromatographic, NMR and vibrational spectroscopic investigations of astaxanthin esters: application to “Astaxanthinrich shrimp oil” obtained from processing of Nordic shrimps. Analyst. 140(21), 7423-7433.

B. Benyelles, H. Allali, N. Fekih, M. Touaibia, A. Muselli, N. Djabou, M. E. Dib, B. Tabti, J. Costa. (2015) Chemical Composition of the Volatile Components of Tropaeolum majus L. (Garden Nasturtium) from North Western Algeria. PhytoChem & BioSub Journal Vol. 9 N° 3, DOI:10.163.pcbsj/2015.9.3.92.

St-Coeur, P-D, Poitras, J.J., Cuperlovic-Culf, M., Touaibia, M., Morin, P. Jr. (2015) Investigating a signature of temozolomide resistance in GBM cell lines using metabolomics. J. Neurooncol. 125: 91-102.

Beauregard AP, Harquail J, Lassalle-Claux G, Belbraouet M, Jean-Francois J, Touaibia M, Robichaud GA. (2015) CAPE Analogs Induce Growth Arrest and Apoptosis in Breast Cancer Cells. Molecules, 20(7),12576-89.

Cuperlovic-Culf, M.; Touaibia, M. (2015) Caffeic acid: Biological Properties, Structure & Health Effects. Chapter 5: Caffeic Acid and its Derivatives as Inhibitors of Lipoxygenases in Different Organisms.
Editor: Leanna Vaughn, Publisher: Nova Science Publishers Inc (Sept. 1 2015). ISBN-10: 1634831217, ISBN-13: 978-1634831215.

Martin J. G. Hébert, Andrew J. Flewelling, Trevor N. Clark, Natalie A. Levesque, Jacques Jean-François, Marc E. Surette, Christopher A. Gray, Christopher M. Vogels, Mohamed Touaibia, and Stephen A. Westcott. (2015) Synthesis and Biological Activity of Arylspiroborate Salts Derived from Caffeic Acid Phenethyl Ester. International Journal of Medicinal Chemistry. In press.

Touaibia, M.; Shiao, T. C.; Roy, R. (2015) Synthesis of Mannopyranoside-Benzo[b]furan analogues through sonogashira coupling and intramolecular dehydrocyclization. Eds.; Taylor & Francis, Carbohydrate Chemistry: Proven Synthetic Methods, 3, Chap. 16, pp. 133-136.

Shiao, T. C.; Sennour, R.; Touaibia, M.; Azzouz, A.; Roy, R. (2015) Lactose-modified triethoxysilane for the surface modification of clay nanocomposites Eds.; Taylor & Francis, Carbohydrate Chemistry: Proven Synthetic Methods 3, Chap. 15, pp. 127-131


Doiron J A. , Métayer B, Richard R R, Desjardins D, Boudreau L H, Levesque N A, Jean-François J, Poirier S J, Surette M E, Touaibia M. (2014) Clicked cinnamic/caffeic esters and amides as radical scavengers and 5-lipoxygenase inhibitors. International Journal of Medicinal Chemistry. ID 931756, 1-12.

Bhullar K S, Lassalle-Claux G, Touaibia M, Rupasinghe H P V (2014) Antihypertensive effect of caffeic acid and its analogs through dual renin angiotensin aldosterone system inhibition. European Journal of Pharmacology. 730, 125-132.

Cuperlovic-Culf, M., Touaibia, M., St-Coeur, P-D, Poitras, J., Morin, P. Jr. et Culf, A. (2014) Metabolic effects of known and novel HDAC and SIRT inhibitors in glioblastomas independently or combined with temozolomide. Metabolites 4: 807-830.

Lefort N, Brown A, Lloyd V, Ouellette R, Touaibia M, Culf AS, Cuperlovic-Culf M. (2014) 1 H NMR metabolomics analysis of the effect of dichloroacetate and allopurinol on breast cancers. Journal of Pharmaceutical and Biomedical Analysis 93, 77-85.


Sanderson J T, Clabault H, Patton C, Lassalle-Claux G, Jean-François J, Paré A F, Hébert M J.G., Surette M E, Touaibia M (2013) Antiproliferative, antiandrogenic and cytotoxic effects of novel caffeic acid derivatives in LNCaP human androgen-dependent prostate cancer cells. Bioorg. Med. Chem. 21(22), 7182-7193.

Roos G, Wellens A, Touaibia M, Yamakawa N, Geerlings P, Roy R, Wyns L, Bouckaert J. (2013) Validation of reactivity descriptors to assess the aromatic stacking within the tyrosine gate of FimH. ACS Medicinal Chemistry letters 4 (11), 1085–1090.

Do, P A; Touaibia, M; Haché, A. (2013) Laser beam diffraction at the edge of a film and application to thin film metrology. Applied Optics 52(24) 5979-5984.

St-Coeur, P-D, Touaibia, M., Cuperlovic-Culf, M. et Morin, P. Jr. (2013) Leveraging metabolomics to assess the next generation of temozolomide-based therapeutic approaches for glioblastomas. Genomics, Proteomics & Bioinformatics 11, 199-206.

St-Coeur, P-D, Ferguson, D., Morin, P. Jr. et Touaibia, M. (2013) PF-8380 and closely related analogues synthesis, structure-activity relationship towards autotaxin inhibition and glioma cell viability. Archiv. Pharm. Chem. Life Sci. 346: 91-97.

Morin, P. Jr., Ferguson, D., LeBlanc, L., Hébert, M., Paré, A., Jean-François, J., Surette, M., Touaibia, M., Cuperlovic-Culf, M. (2013) NMR metabolomics analysis of the effects of 5-lipoxygenase inhibitors on metabolism in glioblastomas. J. Proteome Res. 12: 2165-2176.

Cuperlovic-Culf, M., Culf, A.S, Morin, P. Jr. et Touaibia, M. (2013) Application of metabolomics in drug discovery, development and theranostics. Curr. Metabol. 1: 41-57.


Leblanc LM, Paré AF, Jean-François J, Hébert MJ, Surette ME, Touaibia M. (2012) Synthesis and antiradical/antioxidant activities of caffeic Acid phenethyl ester and its related propionic, acetic, and benzoic Acid analogues. Molecules 17(12):14637-50

Shiao, T. C.; Rodrigue, J.; Touaibia, M. (2012) Synthesis by "Click Chemistry" of an α-D-Mannopyranoside Having a 1,4-Disubstituted Triazole Aglycone. Carbohydrate Chemistry: Proven Methods. CRC Press, vol.1, pp. 91-94.

Shiao, T. C.; Giguère, D.; Touaibia, M. (2012) Palladium-catalyzed Sonogashira Coupling on p-Iodophenyl α-D- Mannopyranoside. Carbohydrate Chemistry: Proven Methods. CRC Press, vol.1, pp. 95-98.

Boudreau, L.H. ; Maillet, J.; LeBlanc, L.M.; Jean-Francois, J.; Touaibia, M.; Flamand, N.; Surette, M.E. (2012) Caffeic acid phenethyl ester and its amide analogue are potent inhibitors of leukotriene biosynthesis in human blood and isolated polymorphonuclear leukocytes. PLoS ONE, 7(2), e31833.

Wellens A, Lahmann M, Touaibia M, Vaucher J, Oscarson S, Roy R, Remaut H, Bouckaert J. (2012) The tyrosine gate as a potential entropic lever in the receptor-binding site of the bacterial adhesin FimH. Biochemistry 51(24):4790-9.

Cuperlovic-Culf, M ; Culf, AS ; Touaibia M; Lefort, N. (2012) Targeting the latest hallmark of cancer: another attempt at 'magic bullet' drugs targeting cancers' metabolic phenotype. Future Oncology 8 (10), 1315-1330.

Andre, S; Canada, FJ; Shiao, TC ; Largartera, L ; Diercks, T ; Bergeron-Brlek, M ; el Biari, K ; Papadopoulos, A ; Ribeiro, JP ; Touaibia M; Solis, D; Menendez, M ; Jimenez-Barbero, J ; Roy, R; Gabius, HJ. (2012) Fluorinated Carbohydrates as Lectin Ligands: Biorelevant Sensors with Capacity to Monitor Anomer Affinity in F-19-NMR-Based Inhibitor Screening. Eur. J. Org. Chem., 23, 4354-4364.


Cuperlovic-Culf, M.; Chute, I.C.; Culf, A.S.; Touaibia, M.; Ghosh, A.; Griffiths, S.; Tulpan, D.; Léger, S.; Belkaid, A.; Surette, M.E.; Ouellette, R.J. (2011) 1H NMR metabolomics combined with gene expression analysis for the determination of major metabolic differences between subtypes of breast cell lines. Chemical Science, DOI: 10.1039/c1sc00382h (in press).

Doiron, J.; Soultan, A.; Richard, R.; Touré, M.M.; Picot, N.; Richard, R.; Čuperlović-Culf, M.; Robichaud, G.A.; Touaibia, M. (2011) Synthesis and structure-activity relationship of 1- and 2-substituted-1,2,3-triazole letrozole-based analogues as aromatase inhibitors. European Journal of Medicinal Chemistry , 46, 4010-4024.

Touaibia, M.; Jean-François, J.; Doiron, J. (2011) Caffeic Acid, a versatile pharmacophore: An overview. Mini-Reviews in Medicinal Chemistry 11 (8), 695-713.

Touaibia, M.; Guay, M.(2011) Natural Product Total Synthesis in the Organic Laboratory: Total Synthesis of Caffeic Acid Phenethyl Ester (CAPE), A Potent 5-Lipoxygenase Inhibitor from Honeybee Hives. J. Chem. Edu. 88 (4), 473-475.

Compositions comprising caffeic acid phenethyl ester analogs for inhibiting blood cell growth.
Murugesan, Alli; Reiman, Anthony; Touaibia, Mohamed
World Intellectual Property Organization, WO2020210920 A1 2020-10-22 

Compositions and methods for inhibiting blood cancer cell growth using a caffeic acid phenethyl ester analog.
Murugesan, Alli; Reiman, Anthony; Touaibia, Mohamed
World Intellectual Property Organization, WO2019075549 A1 2019-04-25 

Preparation of substituted phenols as modulators of lipoxygenase and cyclooxygenase enzyme activity.
Touaibia, Mohamed; Surette, Marc Edgar
World Intellectual Property Organization, WO2017147718 A1 2017-09-08